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Often called the "master antioxidant," it is produced naturally in the body and is found in high concentrations in the liver, where it drives critical detoxification processes

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Cell Rep (2021) 35(11):109235

Reactive oxygen species (ROS) and lipid peroxidation-derived reactive aldehydes (HNE and MDA) have the potential to cause protein medications and neoantigen formation, which will activate antigen presentation cells including dendritic cells (DCs) and macrophages (M), that consequently promote activation of T and B cells